Reciprocal regulation of NF-kB (Relish) and Subolesin in the tick vector, Ixodes scapularis.
BackgroundTick Subolesin and its ortholog in insects and vertebrates, Akirin, have been suggested to play a role in the immune response through regulation of nuclear factor-kappa B (NF-kB)-dependent and independent gene expression via interaction with intermediate proteins that interact with mvs10 scooter NF-kB and other regulatory proteins, bind D